Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19480148 | 1.00 | IGF2R (0.46) | IGF2RMEN1KMT2AGJA1GJB2 | |
| SCHEMBL19480243 | 0.95 | IGF2R (0.42) | IGF2RMEN1KMT2AGJA1GJB2 | |
| SCHEMBL16587627 | 0.93 | AMY1A (0.47) | IGF2RALDH1A1SELEAMY1ASTAT3 | |
| SCHEMBL16869952 | 0.93 | AMY1A (0.47) | IGF2RALDH1A1SELEAMY1ASTAT3 | |
| SCHEMBL22026382 | 0.92 | IGF2R (0.48) | IGF2RMEN1KMT2ASELEL3MBTL1 | |
| SCHEMBL26032277 | 0.90 | AMY1A (0.54) | IGF2RMEN1KMT2AALDH1A1SELE | |
| SCHEMBL27279098 | 0.89 | AMY1A (0.51) | IGF2RMEN1KMT2ASELEAMY1A | |
| SCHEMBL14616228 | 0.89 | AMY1A (0.44) | IGF2RALDH1A1SELEAMY1ASTAT3 | |
| SCHEMBL16587625 | 0.84 | SELE (0.48) | IGF2RMEN1KMT2ASELEL3MBTL1 | |
| SCHEMBL20964722 | 0.83 | L3MBTL1 (0.46) | IGF2RMEN1KMT2AGJA1GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017181193-A2 | METHODS AND COMPOUNDS FOR STIMULATING READ-THROUGH OF PREMATURE TERMINATION CODONS | THE UAB RESEARCH FOUNDATION (US) | 2017-10-19 | — | — | WO | disclosed |