Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612256 | 0.71 | MEN1 (0.39) | ALDH1A1SLC6A9KMT2AGSK3AGSK3B | |
| SCHEMBL6561912 | 0.69 | ALDH1A1 (0.37) | ALDH1A1HTTGSK3AGSK3BCACNA1B | |
| SCHEMBL20188998 | 0.68 | KDM4E (0.48) | KDM4EMDM2S1PR1ALDH1A1TSHR | |
| SCHEMBL20457594 | 0.68 | ALDH1A1 (0.58) | KDM4EMDM2S1PR1ALDH1A1SLC6A9 | |
| SCHEMBL20200101 | 0.67 | HSD17B10 (0.39) | KDM4EMDM2S1PR1ALDH1A1TSHR | |
| SCHEMBL29834060 | 0.67 | KDM4E (0.47) | KDM4EMDM2S1PR1ALDH1A1TSHR | |
| Tetraxetan SCHEMBL5370171 | 0.67 | HSD17B10 (0.58) | KDM4ES1PR1ALDH1A1SLC6A9KMT2A | |
| SCHEMBL31679390 | 0.67 | HSD17B10 (0.45) | KDM4EMDM2S1PR1ALDH1A1SLC6A9 | |
| SCHEMBL31679340 | 0.67 | HSD17B10 (0.45) | KDM4EMDM2S1PR1ALDH1A1SLC6A9 | |
| SCHEMBL6848102 | 0.66 | HSD17B10 (0.64) | KDM4ES1PR1ALDH1A1TSHRSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992886-B2 | Cyclic peptide analogues for non-invasive imaging of pancreatic beta-cells | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-03-31 | — | — | US | disclosed |