Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127624 | 0.80 | SIGMAR1 (0.45) | MEN1ALDH1A1POLBKMT2ASIGMAR1 | |
| SCHEMBL9610827 | 0.76 | PTGS1 (0.57) | ALDH1A1PTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL22954477 | 0.74 | SIGMAR1 (0.41) | MEN1ALDH1A1POLBKMT2ASIGMAR1 | |
| SCHEMBL22954478 | 0.74 | SIGMAR1 (0.41) | MEN1ALDH1A1POLBKMT2ASIGMAR1 | |
| SCHEMBL22779178 | 0.72 | SLC6A9 (0.42) | ALDH1A1PTGS1PTGS2SLC6A9FAAH | |
| SCHEMBL22354597 | 0.72 | SLC6A9 (0.42) | ALDH1A1PTGS1PTGS2SLC6A9FAAH | |
| SCHEMBL20187636 | 0.72 | HSD17B10 (0.42) | MEN1ALDH1A1POLBKMT2ASIGMAR1 | |
| SCHEMBL18118450 | 0.72 | MGLL (0.45) | ALDH1A1PTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL16588917 | 0.71 | KDM4E (0.39) | MEN1ALDH1A1POLBKMT2AGSK3A | |
| SCHEMBL1064815 | 0.71 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651411-B1 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | IMMUNOMEDICS, INC. | 2016-07-14 | — | — | US | disclosed |
| US-20150307524-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2015-10-29 | — | — | US | disclosed |
| US-9115172-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-9028800-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20150057432-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20140377177-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2014-12-25 | — | — | US | disclosed |
| US-8889100-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140228541-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8758726-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8709382-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8545809-B2 | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057432-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | MEN1 108/4885ALDH1A1 4430/4885POLB 1864/4885 |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | BRS3, BRCA1, MRE11 | MEN1 93/4885ALDH1A1 3300/4885POLB 1787/4885 |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | MEN1 211/4885ALDH1A1 4559/4885POLB 2151/4885 |
| US-20140228541-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | MEN1 108/4885ALDH1A1 4430/4885POLB 1864/4885 |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | MEN1 211/4885ALDH1A1 4559/4885POLB 2151/4885 |
| US-20150307524-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | MEN1 108/4885ALDH1A1 4430/4885POLB 1864/4885 |
| US-20140377177-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | MEN1 211/4885ALDH1A1 4559/4885POLB 2151/4885 |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | MEN1 108/4885ALDH1A1 4430/4885POLB 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.