SCHEMBL1658906

SCHEMBL1658906

NCCC(N)C(=O)OC(=O)C(N)CN

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.35
DPP7 Q9UHL4 6/20 0.35
RRM1 P23921 1/20 0.34
GABRR1 P24046 2/20 0.33
DPP8 Q6V1X1 3/20 0.32
DPP9 Q86TI2 3/20 0.32
DPP4 P27487 1/20 0.31
FAP Q12884 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9902389 0.87 GSR (0.47) GSRDPP7DPP8DPP9DPP4
SCHEMBL4702268 0.83 DPP7 (0.41) GSRDPP7RRM1GABRR1DPP8
SCHEMBL20636766 0.80 DPP7 (0.38) GSRDPP7RRM1GABRR1DPP8
SCHEMBL29075853 0.79 GSR (0.52) GSRDPP7DPP8DPP9DPP4
SCHEMBL997560 0.79 GSR (0.52) GSRDPP7DPP8DPP9DPP4
SCHEMBL1537223 0.79 GSR (0.52) GSRDPP7DPP8DPP9DPP4
SCHEMBL11531701 0.78 RNPEP (0.37)
SCHEMBL20240364 0.77 GSR (0.61) GSRDPP7DPP8DPP9DPP4
SCHEMBL16528819 0.77 ALDH1A1 (0.33)
SCHEMBL344574 0.77 GSR (0.61) GSRDPP7DPP8DPP9DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
US-20180243441-A1 CYTOTOXIC HEXIM1 PEPTIDES AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-08-30 US disclosed
EP-3265472-A1 CYTOTOXIC HEXIM1 PEPTIDES AND USES THEREOF Agency For Science, Technology And Research (SG) 2018-01-10 EP disclosed
US-9012567-B2 Supramolecular polymers and compositions containing said polymers RHODIA OPERATIONS (FR) 2015-04-21 US disclosed
US-20120289652-A1 SUPRAMOLECULAR POLYMERS AND COMPOSITIONS CONTAINING SAID POLYMERS RHODIA OPERATIONS (FR) 2012-11-15 US disclosed
WO-2011047241-A1 ENHANCED SUBSTRATES FOR THE PROTEASE ACTIVITY OF SEROTYPE A BOTULINUM NEUROTOXIN DEPARTMENT OF THE US ARMY (US) 2011-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180243441-A1 CYTOTOXIC HEXIM1 PEPTIDES AND USES THEREOF IGF2BP1, L3MBTL1, MYADM GSR 4541/4885DPP7 822/4885RRM1 3417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.