Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.78 |
| ▸ | HTR1A | P08908 | 5/20 | 0.78 |
| ▸ | HTR2A | P28223 | 5/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | HTR2B | P41595 | 4/20 | 0.78 |
| ▸ | BLM | P54132 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.78 |
| ▸ | HTR7 | P34969 | 2/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | MTOR | P42345 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176550 | 1.00 | HTR2C (0.78) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| SCHEMBL24451374 | 0.88 | HTR2A (0.77) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| Oxitriptan SCHEMBL28924441 | 0.88 | NPSR1 (0.95) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| SCHEMBL17640312 | 0.88 | HTR2A (0.77) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| SCHEMBL5066582 | 0.87 | HTR2C (0.80) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| Oxitriptan SCHEMBL21114382 | 0.87 | NPSR1 (1.00) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| Oxitriptan SCHEMBL19871232 | 0.87 | NPSR1 (1.00) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| Oxitriptan SCHEMBL21114383 | 0.87 | NPSR1 (1.00) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| Oxitriptan SCHEMBL1421238 | 0.87 | NPSR1 (1.00) | HTR2CNPSR1HTR1AHTR2AKDM4E | |
| Oxitriptan SCHEMBL3033706 | 0.87 | NPSR1 (1.00) | HTR2CNPSR1HTR1AHTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481383-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | CELLIX BIO PRIVATE LTD (IN) | 2023-06-14 | — | — | EP | disclosed |
| US-20150291590-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES | CELLIX BIO PRIVATE LTD (IN) | 2015-10-15 | — | — | US | disclosed |
| US-20150087697-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCLE PAIN | KANDULA MAHESH (IN) | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291590-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES | KYNU, TKT, SLC5A1 | HTR2C 587/4885NPSR1 2757/4885HTR1A 577/4885 |
| US-20150087697-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUSCLE PAIN | TNNC1, MUSK, OPRK1 | HTR2C 507/4885NPSR1 161/4885HTR1A 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.