Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671160 | 1.00 | HPGD (0.76) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10581544 | 1.00 | HPGD (0.76) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28347915 | 1.00 | HPGD (0.76) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11928065 | 0.98 | HPGD (0.78) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10913949 | 0.93 | HPGD (0.70) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL13109349 | 0.91 | SOAT2 (0.75) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3448581 | 0.91 | SOAT2 (0.75) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3448583 | 0.91 | SOAT2 (0.75) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28347772 | 0.90 | HPGD (0.64) | HPGDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18328436 | 0.89 | HPGD (0.62) | HPGDHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303493-A1 | ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF | SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| US-20230303493-A1 | ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF | SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| CN-106822895-A | Photoresponse liposome and its preparation method and application | 深圳市前海安测信息技术有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106800521-A | Azobenzene derivatives and its preparation method and application | 深圳市易特科信息技术有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-106692058-A | Azobenzene derivative containing lipidosome as well as preparation method and application thereof | 深圳市易特科信息技术有限公司 | 2017-05-24 | — | — | CN | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
| WO-2015042363-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-03-26 | — | — | WO | disclosed |
| US-8952016-B2 | Substituted xanthine derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2015-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | BLVRB, PGLS, GRHPR | HPGD 481/4885HDAC3 3253/4885HDAC1 3127/4885 |
| US-20230303493-A1 | ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF | CAPG, SLC11A2, CAPRIN1 | HPGD 2173/4885HDAC3 3915/4885HDAC1 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.