SCHEMBL1660019

SCHEMBL1660019

CCC(C)C(C)CCCCO

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 3/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5354545 0.97 LMNA (0.43) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1658309 0.97 LMNA (0.43) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1052850 0.92 ALDH1A1 (0.38) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1658244 0.84 SMN1; SMN2 (0.48) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL6003917 0.83 SMN1; SMN2 (0.38) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL6242394 0.82 LMNA (0.50) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL1442505 0.80
SCHEMBL13378306 0.80 SMN1; SMN2 (0.38) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL11730826 0.80 TSHR (0.50) LMNAALDH1A1TSHR
SCHEMBL9720187 0.80 ALDH1A1 (0.39) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926474-B2 Pressure-sensitive adhesive compositions and adhesive articles including the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-27 US disclosed
EP-2951257-B1 PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS AND ADHESIVE ARTICLES INCLUDING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2017-01-04 EP disclosed
EP-2951257-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS AND ADHESIVE ARTICLES INCLUDING THE SAME 3M Innovative Properties Company (US) 2015-12-09 EP disclosed
WO-2014120593-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS AND ADHESIVE ARTICLES INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-07 WO disclosed
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20130131169-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-23 US disclosed
US-8377458-B2 Cooling sensation agent composition, sensory stimulation agent composition and use of the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-02-19 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
US-20110081393-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TAKASAGO INTERNATIONAL CORPORATION 2011-04-07 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 SMN1; SMN2 2144/4885LMNA 1708/4885ALDH1A1 520/4885
US-20110081393-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TRPA1, TRPV1, TRPM4 SMN1; SMN2 2797/4885LMNA 1727/4885ALDH1A1 685/4885
US-20130131169-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TRPA1, TRPV1, TRPM4 SMN1; SMN2 2797/4885LMNA 1727/4885ALDH1A1 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.