SCHEMBL16600191

SCHEMBL16600191

C[Si](C)(C)c1cc(Br)c([Si](C)(C)C)cc1Br

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16682941 0.87 TSHR (0.36)
SCHEMBL23611585 0.81
SCHEMBL29877583 0.81
SCHEMBL9504603 0.81
SCHEMBL12403115 0.77
SCHEMBL19126026 0.75 HSP90AA1 (0.41) AHR
SCHEMBL31277494 0.73 KDM1A (0.33)
SCHEMBL8861704 0.72 ENPP2 (0.35)
SCHEMBL17866559 0.72 AHR (0.34) AHR
SCHEMBL13650780 0.72 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840460-B2 Azaborinine derivatives, their synthesis and use in organic electronic devices FLEXENABLE LIMITED (GB) 2020-11-17 US disclosed
EP-3052506-B1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES FLEXENABLE LTD (GB) 2020-06-03 EP disclosed
EP-3052506-B1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES FLEXENABLE LTD (GB) 2020-06-03 EP disclosed
EP-3195378-B1 HOLE TRANSPORTING COMPOSITIONS CAMBRIDGE DISPLAY TECH LTD (GB) 2019-08-21 EP disclosed
EP-3195379-B1 HOLE TRANSPORTING CYCLOBUTENE COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2019-08-21 EP disclosed
US-9929347-B2 Polymer compound and light emitting element using same SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2018-03-27 US disclosed
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
US-20170207394-A1 HOLE TRANSPORTING CYCLOBUTENE COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
US-20160248014-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-08-25 US disclosed
US-20160248014-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-08-25 US disclosed
US-20160248014-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-08-25 US disclosed
EP-3052506-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES Merck Patent GmbH (DE) 2016-08-10 EP disclosed
US-20150115204-A1 POLYMER COMPOUND AND LIGHT EMITTING ELEMENT USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-04-30 US disclosed
US-20150115204-A1 POLYMER COMPOUND AND LIGHT EMITTING ELEMENT USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-04-30 US disclosed
WO-2015043722-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-02 WO disclosed
WO-2015043722-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10840460-B2 Azaborinine derivatives, their synthesis and use in organic electronic devices AZI2, NME2, ALKBH2 AHR 1372/4885
US-20160248014-A1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES AZI2, NME2, ALKBH2 AHR 1372/4885
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS SP1, NR0B1, C1S AHR 30/4885
US-20170207394-A1 HOLE TRANSPORTING CYCLOBUTENE COMPOUND SP1, NR0B1, CCNT1 AHR 36/4885
US-20150115204-A1 POLYMER COMPOUND AND LIGHT EMITTING ELEMENT USING SAME NAP1L4, AHR, NR0B1 AHR 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.