Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.39 |
| ▸ | MGAM | O43451 | 8/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.39 |
| ▸ | SI | P14410 | 8/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | F12 | P00748 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617481 | 0.79 | KDM4E (0.40) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7636077 | 0.76 | GAA (0.36) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2113290 | 0.74 | MAPK1 (0.48) | DGAT1KDM4EMAPT | |
| SCHEMBL451898 | 0.72 | GAA (0.37) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL170673 | 0.71 | GAA (0.71) | GAAMGAMAMY1ASIMGAM2 | |
| Ammonia Solution, Strong SCHEMBL3505685 | 0.69 | GAA (0.69) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL8907627 | 0.68 | KCNMA1 (0.45) | GAAMGAMAMY1ASIMGAM2 | |
| Malonic Acid SCHEMBL8211367 | 0.64 | GAA (0.61) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL4310543 | 0.64 | KDM4E (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9952327 | 0.64 | ELANE (0.45) | F2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049390-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015044163-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |