Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SI | P14410 | 3/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775814 | 0.78 | FAAH (0.40) | KCNMA1KDM4EL3MBTL1CHRM1FAAH | |
| SCHEMBL3767410 | 0.77 | ACHE (0.39) | KCNMA1KDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL4066804 | 0.75 | MAPT (0.48) | KMT2AHPGDMAPT | |
| SCHEMBL378660 | 0.75 | POLB (0.50) | KCNMA1KDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL8425686 | 0.73 | ACHE (0.39) | KCNMA1KDM4EL3MBTL1KDM4ARAB9A | |
| Water SCHEMBL3673310 | 0.73 | POLB (0.48) | KCNMA1KDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL10734042 | 0.73 | SLC9A1 (0.48) | KCNMA1KDM4ERAB9AGAAKMT2A | |
| SCHEMBL8146888 | 0.73 | MAPT (0.48) | KCNMA1KDM4EL3MBTL1KDM4ARAB9A | |
| SCHEMBL706083 | 0.71 | MGAM (0.68) | KCNMA1KDM4EMGAMAMY1AGAA | |
| SCHEMBL8933923 | 0.70 | RAB9A (0.36) | KCNMA1KDM4EL3MBTL1KDM4ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672605-A | ADMINISTERING TO TREAT AUTOIMMUNE DISORDERS, TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 1997-09-30 | — | — | US | disclosed |
| US-5583139-A | Marcolide immunomodulators | ABBOTT LABORATORIES (US) | 1996-12-10 | — | — | US | disclosed |
| US-5527907-A | IMMUNOSUPPRESSANTS | ABBOTT LABORATORIES (US) | 1996-06-18 | — | — | US | disclosed |