SCHEMBL1660106

SCHEMBL1660106

Oc1cc(C(F)(F)F)ccn1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.57
NOS2 P35228 1/20 0.57
ADRB1 P08588 1/20 0.43
ADRB2 P07550 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CES2 O00748 3/20 0.39
KMO O15229 1/20 0.38
MAP2K4 P45985 1/20 0.38
MAPKAPK2 P49137 1/20 0.38
MAPKAPK3 Q16644 1/20 0.38
MAPK6 Q16659 1/20 0.38
NPC1 O15118 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30947607 1.00 NOS3 (0.57) NOS3NOS2ADRB1ADRB2KDM4E
SCHEMBL30947602 0.83 NOS3 (0.39) NOS3NOS2ADRB1ADRB2ALDH1A1
SCHEMBL13971495 0.83 NOS3 (0.39) NOS3NOS2ADRB1ADRB2ALDH1A1
SCHEMBL803429 0.77 ALDH1A1 (0.46) NOS3NOS2ADRB2KDM4EALDH1A1
SCHEMBL8764962 0.77 TSHR (0.38) NOS3NOS2
SCHEMBL810884 0.76 NOS3 (0.61) NOS3NOS2ADRB1ADRB2MAPK1
SCHEMBL29518423 0.74 NOS3 (0.59) NOS3NOS2ADRB1ADRB2MAPK1
SCHEMBL2327508 0.74 NOS3 (0.59) NOS3NOS2ADRB1ADRB2MAPK1
SCHEMBL607015 0.74 NOS3 (0.59) NOS3NOS2ADRB1ADRB2MAPK1
SCHEMBL29553421 0.74 NOS3 (0.48) NOS3NOS2ADRB2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286568-B Preparation method of 2-hydroxy-4-trifluoromethyl pyridine 常州沃腾化工科技有限公司 2023-12-12 CN claimed
CN-116425671-A Synthesis method of 2-chloro-4- (trifluoromethyl) pyridine 江苏省农用激素工程技术研究中心有限公司 2023-07-14 CN claimed
CN-113773246-B Preparation method of 2-substituted-4-trifluoromethylpyridine 山东省农药科学研究院 2023-03-31 CN claimed
CN-115385852-A Efficient synthesis method of 2-amino-4-trifluoromethylpyridine 湖南阿斯迪康药业有限公司 2022-11-25 CN claimed
CN-115286568-A Preparation method of 2-hydroxy-4-trifluoromethylpyridine 常州沃腾化工科技有限公司 2022-11-04 CN claimed
CN-113292487-B Preparation method of pyroxsulam intermediate 江苏省农用激素工程技术研究中心有限公司 2022-04-08 CN claimed
CN-113773246-A Preparation method of 2-substituted-4-trifluoromethylpyridine 山东省农药科学研究院 2021-12-10 CN claimed
CN-113292487-A Preparation method of pyroxsulam intermediate 江苏省农用激素工程技术研究中心有限公司 2021-08-24 CN claimed
EP-1723156-B1 PROCESS FOR THE PREPARATION OF PYRIDINE DERIVATIVES DOW AGROSCIENCES LLC (US) 2015-01-21 EP claimed
US-8501595-B2 Thin film containing nanocrystal particles and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-08-06 US claimed
US-7633087-B2 Semiconductor thin film using self-assembled monolayers and methods of production thereof SAMSUNG CORNING PRECISION GLASS CO., LTD. (KR) 2009-12-15 US claimed
US-20070298160-A1 THIN FILM CONTAINING NANOCRYSTAL PARTICLES AND METHOD FOR PREPARING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-12-27 US claimed
US-20070166645-A1 Chalcogenide precursor compound and method for preparing chalcogenide thin film using the same SAMSUNG CORNING PRECISION GLASS CO., LTD. (KR) 2007-07-19 US claimed
US-20070117279-A1 Semiconductor thin film using self-assembled monolayers and methods of production thereof CORNING PRECISION MATERIALS CO., LTD. (KR) 2007-05-24 US claimed
US-20070090346-A1 Porous chalcogenide thin film, method for preparing the same and electronic device using the same SAMSUNG CORNING PRECISION GLASS CO., LTD. (KR) 2007-04-26 US claimed
EP-3773573-B1 ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) MORPHIC THERAPEUTIC INC (US) 2026-03-18 EP disclosed
US-12384790-B2 Pteridinone compounds and uses thereof VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-08-12 US disclosed
EP-0778267-A1 SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-11 EP disclosed
US-5238906-A Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-24 US disclosed
EP-0488220-A2 Pyridone derivatives, and their production and use SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1992-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070090346-A1 Porous chalcogenide thin film, method for preparing the same and electronic device using the same STOM, PROX1, HCN4 NOS3 1449/4885NOS2 608/4885ADRB1 4882/4885
US-12384790-B2 Pteridinone compounds and uses thereof DPYD, PKD1, TYMP NOS3 2453/4885NOS2 2057/4885ADRB1 2811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.