SCHEMBL607015

SCHEMBL607015

Fc1cc(C(F)(F)F)ccn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.59
NOS2 P35228 1/20 0.59
SYK P43405 2/20 0.47
S1PR1 P21453 1/20 0.46
ADRB1 P08588 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.43
MAPK14 Q16539 3/20 0.41
MAPK1 P28482 2/20 0.41
ADRB2 P07550 1/20 0.40
KIF11 P52732 2/20 0.38
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
AURKA O14965 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
TDO2 P48775 1/20 0.36
IDO1 P14902 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518423 1.00 NOS3 (0.59) NOS3NOS2SYKS1PR1ADRB1
SCHEMBL1437267 0.82 MKNK1 (0.42) NOS3NOS2SYKS1PR1ADRB1
SCHEMBL30947579 0.82 MKNK1 (0.42) NOS3NOS2SYKS1PR1ADRB1
SCHEMBL21554355 0.80 MKNK1 (0.44) NOS3NOS2SYKS1PR1ADRB1
SCHEMBL6371369 0.79 MKNK1 (0.43) NOS3NOS2SYKS1PR1LOXL2
SCHEMBL16472120 0.79 MKNK1 (0.43) NOS3NOS2SYKS1PR1LOXL2
SCHEMBL7693999 0.79 LOXL2 (0.42) NOS3NOS2SYKS1PR1LOXL2
SCHEMBL810884 0.78 NOS3 (0.61) NOS3NOS2SYKADRB1MAPK1
SCHEMBL6186146 0.78 PNMT (0.43) NOS3NOS2LOXL2MAPK14MAPK1
SCHEMBL27144506 0.77 LOXL2 (0.41) NOS3NOS2SYKS1PR1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114361590-B Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery 松山湖材料实验室 2023-07-25 CN claimed
CN-116283515-A Direct cross coupling method of aryl fluoride and aryl bromide 南京工业大学 2023-06-23 CN claimed
CN-114361590-A Lithium ion battery electrolyte additive, electrolyte and lithium ion battery 松山湖材料实验室 2022-04-15 CN claimed
EP-4745129-A2 COMPOUND HAVING CYCLIC STRUCTURE Daiichi Sankyo Company, Limited (JP) 2026-05-20 EP disclosed
EP-3682881-B1 COMPOUND HAVING CYCLIC STRUCTURE DAIICHI SANKYO CO LTD (JP) 2026-04-01 EP disclosed
EP-4688155-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS Bial-Portela & CA, S.A. (PT) 2026-02-11 EP disclosed
EP-4688154-A1 MORPHOLINE OREXIN RECEPTOR ANTAGONISTS BIAL - Portela & Ca., S.A. (PT) 2026-02-11 EP disclosed
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-12441725-B2 ISO-citrate dehydrogenase (IDH) inhibitor ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) 2025-10-14 US disclosed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
US-20250230172-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF VANQUA BIO, INC. (US) 2025-07-17 US disclosed
US-20110054173-A1 PTERIDINES AND THEIR USE AS AGROCHEMICALS DOW AGROSCIENCES LLC (US) 2011-03-03 US disclosed
US-20110054173-A1 PTERIDINES AND THEIR USE AS AGROCHEMICALS DOW AGROSCIENCES LLC (US) 2011-03-03 US disclosed
US-20110054173-A1 PTERIDINES AND THEIR USE AS AGROCHEMICALS DOW AGROSCIENCES LLC (US) 2011-03-03 US disclosed
WO-2011025505-A1 PTERIDINES AND THEIR USE AS AGROCHEMICALS DOW AGROSCIENCES LLC (US) 2011-03-03 WO disclosed
WO-2010122151-A1 3 -AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS GLAXO GROUP LIMITED (GB) 2010-10-28 WO disclosed
WO-2010025451-A2 5,8-DIFLUORO-4-(2-(4-(HETEROARYLOXY)-PHENYL)ETHYLAMINO)QUINAZOLINES AND THEIR USE AS AGROCHEMICALS DOW AGROSCIENCES LLC (US) 2010-03-04 WO disclosed
US-20100056374-A1 5,8-DIFLUORO-4-(2-(4-(HETEROARYLOXY)-PHENYL)ETHYLAMINO)QUINAZOLINES AND THEIR USE AS AGROCHEMICALS DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
WO-2002020487-A1 SUBSTITUTED 1-ARYL-PYRIDIN-2-(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2002-03-14 WO disclosed
US-4775762-A INSECTICIDES THE DOW CHEMICAL COMPANY (US) 1988-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS ASGR1, ENGASE, FCGR2A NOS3 4647/4885NOS2 4561/4885SYK 2329/4885
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 NOS3 2789/4885NOS2 2444/4885SYK 2318/4885
US-20100056374-A1 5,8-DIFLUORO-4-(2-(4-(HETEROARYLOXY)-PHENYL)ETHYLAMINO)QUINAZOLINES AND THEIR USE AS AGROCHEMICALS NQO2, DDT, RAB7A NOS3 2296/4885NOS2 3045/4885SYK 4361/4885
US-20250230172-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF GBA1, GAA, GBA2 NOS3 3516/4885NOS2 3902/4885SYK 3241/4885
US-20110054173-A1 PTERIDINES AND THEIR USE AS AGROCHEMICALS PIR, PFAS, PNPO NOS3 1946/4885NOS2 2222/4885SYK 3301/4885
US-12441725-B2 ISO-citrate dehydrogenase (IDH) inhibitor IDH2, IDH3A, IDH1 NOS3 2641/4885NOS2 2010/4885SYK 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.