Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947607 | 0.77 | NOS3 (0.57) | NOS3NOS2 | |
| SCHEMBL803429 | 0.77 | ALDH1A1 (0.46) | RECQLNOS3NOS2 | |
| SCHEMBL1660106 | 0.77 | NOS3 (0.57) | NOS3NOS2 | |
| SCHEMBL6280836 | 0.74 | RECQL (0.48) | TSHRRECQLNOS3NOS2 | |
| SCHEMBL13971495 | 0.74 | NOS3 (0.39) | NOS3NOS2 | |
| SCHEMBL30947602 | 0.74 | NOS3 (0.39) | NOS3NOS2 | |
| SCHEMBL8764956 | 0.73 | TSHR (0.38) | TSHRNOS3NOS2 | |
| SCHEMBL7693999 | 0.73 | LOXL2 (0.42) | TSHRNOS3NOS2 | |
| SCHEMBL9474492 | 0.73 | NOS3 (0.63) | TSHRNOS3NOS2 | |
| SCHEMBL18745357 | 0.72 | MAPK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |