Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913702 | 0.81 | MAOB (0.39) | MAOBTAAR1ALDH1A1IDO1AGXT | |
| SCHEMBL2414804 | 0.81 | MAOB (0.39) | MAOBTAAR1NPC1ALDH1A1RAB9A | |
| SCHEMBL7877438 | 0.81 | CALM1 (0.41) | CALM1BCL2BCL2L1TAAR1NPC1 | |
| SCHEMBL2093279 | 0.80 | CALM1 (0.50) | CALM1BCL2BCL2L1IDH1LMNA | |
| SCHEMBL4757691 | 0.77 | CALM1 (0.41) | CALM1BCL2BCL2L1TAAR1IDH1 | |
| SCHEMBL2852601 | 0.77 | CALM1 (0.41) | CALM1BCL2BCL2L1NPC1ALDH1A1 | |
| SCHEMBL6981018 | 0.77 | MAOB (0.42) | CALM1MAOBBCL2BCL2L1ALDH1A1 | |
| SCHEMBL7014345 | 0.77 | CALM1 (0.41) | CALM1BCL2BCL2L1ALDH1A1IDH1 | |
| SCHEMBL2154106 | 0.77 | MEN1 (0.44) | CALM1BCL2BCL2L1TAAR1ALDH1A1 | |
| SCHEMBL8602727 | 0.77 | ALOX5 (0.47) | CALM1BCL2BCL2L1IDH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | disclosed |