SCHEMBL16601560

SCHEMBL16601560

NOc1ccc(Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 15/20 0.49
KCNH2 Q12809 6/20 0.49
SCN5A Q14524 5/20 0.49
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NR4A1 P22736 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
TTBK1 Q5TCY1 1/20 0.41
TTBK2 Q6IQ55 1/20 0.41
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122381 0.85
Hydrochloric Acid SCHEMBL1134524 0.83 MAOB (0.50) KDM4EMAPTMAOAMAOBCA1
SCHEMBL1686571 0.80 LMNA (0.57) SCN9ANPC1GAAMAPTMAPK1
SCHEMBL9516529 0.80 LMNA (0.57) SCN9ANPC1GAAMAPTMAPK1
SCHEMBL12443124 0.79 ALDH1A1 (0.62) KDM4ENPC1GAAMAPTTHRB
SCHEMBL9629628 0.77 MAPT (0.77) KDM4ENPC1GAAMAPTTHRB
SCHEMBL16601556 0.77 MAPT (0.44) KDM4ENPC1GAAMAPTTHRB
SCHEMBL16601557 0.77 GAA (0.44) SCN9AKCNH2SCN5AKDM4ENPC1
SCHEMBL16601551 0.77 MAPT (0.44) KCNH2KDM4ENPC1GAAMAPT
SCHEMBL9544540 0.76 SCN9A (0.44) SCN9AKCNH2SCN5AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993086-B2 Recordable optical recording medium TAIYO YUDEN CO., LTD. (JP) 2015-03-31 US disclosed