Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98774 | 0.86 | LMNA (0.47) | MAPTNPC1KDM4ERAB9ATDP1 | |
| SCHEMBL1954439 | 0.79 | CYP1A2 (0.46) | NPC1GAARAB9ANPSR1MEN1 | |
| SCHEMBL1686571 | 0.78 | LMNA (0.57) | SCN9AMAPTNPC1GAAMAPK1 | |
| SCHEMBL9516529 | 0.78 | LMNA (0.57) | SCN9AMAPTNPC1GAAMAPK1 | |
| SCHEMBL16601560 | 0.76 | SCN9A (0.49) | SCN9AKCNH2SCN5AMAPTNPC1 | |
| SCHEMBL9629628 | 0.76 | MAPT (0.77) | MAPTNPC1KDM4EGAATHRB | |
| SCHEMBL13945696 | 0.71 | PPARA (0.47) | SCN9AKCNH2SCN5AMAPTNPC1 | |
| SCHEMBL11201059 | 0.71 | KDM4E (0.62) | MAPTKDM4EGAANPSR1TDP1 | |
| SCHEMBL9166120 | 0.70 | IDO1 (0.42) | MAPTNPC1KDM4EGAATHRB | |
| SCHEMBL9479942 | 0.69 | ALDH1A1 (0.72) | MAPTKDM4ETHRBMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016195-A1 | CHEMILUMINESCENT ENHANCERS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-08-19 | — | — | WO | claimed |
| WO-1993016195-A1 | CHEMILUMINESCENT ENHANCERS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-08-19 | — | — | WO | disclosed |