SCHEMBL16601611

SCHEMBL16601611

CCc1cccc(CC)c1N1C(=O)c2cc(-c3ccccc3)c3c4c(cc(-c5ccccc5)c(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.49
DPP4 P27487 2/20 0.49
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
NPEPPS P55786 1/20 0.37
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
CASP1 P29466 1/20 0.36
BRCA1 P38398 1/20 0.36
CASP7 P55210 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ADK P55263 1/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24977034 0.84 ANPEP (0.35) ANPEPDPP4CRHBPCRHR2NPEPPS
SCHEMBL12107884 0.83 ADK (0.45) MEN1USP2CASP1BRCA1CASP7
SCHEMBL15764203 0.81 ANPEP (0.46) ANPEPDPP4CRHBPCRHR2MAPT
SCHEMBL16656161 0.79 PGR (0.38) ANPEPDPP4MEN1KMT2AMAPT
SCHEMBL16656164 0.78 DPP4 (0.42) ANPEPDPP4CRHBPCRHR2NPEPPS
SCHEMBL16601608 0.77 ANPEP (0.59) ANPEPDPP4CRHBPCRHR2NPEPPS
SCHEMBL16656163 0.76 DPP4 (0.44) ANPEPDPP4CRHBPCRHR2NPEPPS
SCHEMBL21537188 0.74 ALDH1A1 (0.40) MEN1USP2CASP1BRCA1CASP7
SCHEMBL16656331 0.74 DPP4 (0.42) ANPEPDPP4CRHBPCRHR2MEN1
SCHEMBL16601630 0.72 ANPEP (0.54) ANPEPDPP4CRHBPCRHR2NPEPPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed