SCHEMBL16601613

SCHEMBL16601613

COCC(c1ccccc1)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.40
TNF P01375 6/20 0.40
CASP3 P42574 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
OPRL1 P41146 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
USP2 O75604 2/20 0.36
KEAP1 Q14145 2/20 0.36
NFE2L2 Q16236 2/20 0.36
ATM Q13315 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
PDE4A P27815 5/20 0.36
PDE4B Q07343 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13923588 0.84 CASP3 (0.42) PRMT1TNFCASP3OPRM1OPRD1
SCHEMBL24978088 0.83 MEN1 (0.48) TNFCASP3ALDH1A1HSD17B10L3MBTL1
SCHEMBL16601609 0.78 TDP1 (0.44) PRMT1CASP3ALDH1A1L3MBTL1MEN1
SCHEMBL13878052 0.77 ALDH1A1 (0.43) TNFOPRM1OPRD1OPRK1OPRL1
SCHEMBL13923580 0.76 CASP3 (0.46) PRMT1CASP3ALDH1A1MEN1KMT2A
SCHEMBL10018480 0.75 PRMT1 (0.40) PRMT1CASP3ALDH1A1HSD17B10L3MBTL1
SCHEMBL13878068 0.75 ALDH1A1 (0.42) TNFALDH1A1HSD17B10L3MBTL1MEN1
SCHEMBL16601633 0.74 PRMT1 (0.39) PRMT1CASP3ALDH1A1HSD17B10L3MBTL1
SCHEMBL13878060 0.74 MEN1 (0.51) TNFOPRL1ALDH1A1HSD17B10L3MBTL1
SCHEMBL13878066 0.73 TDP1 (0.50) OPRM1OPRD1OPRK1OPRL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed