SCHEMBL16601609

SCHEMBL16601609

COCC(Cc1ccccc1)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 5/20 0.40
GAA P10253 1/20 0.40
TSHR P16473 1/20 0.39
PRMT1 Q99873 1/20 0.39
POLB P06746 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CASP3 P42574 1/20 0.37
AADAT Q8N5Z0 1/20 0.36
HSD11B1 P28845 1/20 0.36
KMT2A Q03164 2/20 0.35
HCRTR2 O43614 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
ATM Q13315 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24977075 0.90 TDP1 (0.43) TDP1ALDH1A1GAATSHRPOLB
SCHEMBL10018480 0.82 PRMT1 (0.40) ALDH1A1PRMT1POLBL3MBTL1CASP3
SCHEMBL16601633 0.81 PRMT1 (0.39) ALDH1A1PRMT1POLBL3MBTL1CASP3
SCHEMBL16601613 0.78 PRMT1 (0.40) TDP1ALDH1A1PRMT1POLBL3MBTL1
SCHEMBL16601984 0.76 TNF (0.39) ALDH1A1PRMT1POLBL3MBTL1KDM4E
SCHEMBL16417482 0.76 ALDH1A1 (0.50) TDP1ALDH1A1GAATSHRPOLB
SCHEMBL16601612 0.75 PRMT1 (0.35) ALDH1A1PRMT1POLBL3MBTL1CASP3
SCHEMBL21226294 0.72 ALDH1A1 (0.47) TDP1ALDH1A1GAATSHRPOLB
SCHEMBL16656201 0.72 TDP1 (0.49) TDP1ALDH1A1GAAPOLBL3MBTL1
SCHEMBL16656165 0.72 CASP3 (0.41) ALDH1A1PRMT1POLBL3MBTL1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed