SCHEMBL16601633

SCHEMBL16601633

COCC(CC(C)C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.39
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 4/20 0.35
KEAP1 Q14145 3/20 0.35
NFE2L2 Q16236 3/20 0.35
USP2 O75604 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
ATM Q13315 1/20 0.35
TERT O14746 3/20 0.34
CASP3 P42574 1/20 0.34
CLK1 P49759 2/20 0.34
DYRK1A Q13627 2/20 0.34
CLK4 Q9HAZ1 2/20 0.34
DYRK1B Q9Y463 2/20 0.34
POLB P06746 1/20 0.33
TYMS P04818 1/20 0.33
MAPT P10636 2/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10018480 0.87 PRMT1 (0.40) PRMT1MEN1KMT2AALDH1A1KEAP1
SCHEMBL701659 0.83 TDP1 (0.45) MEN1KMT2AALDH1A1HPGDPOLB
SCHEMBL16656192 0.83 ALDH1A1 (0.37) PRMT1MEN1KMT2AALDH1A1KEAP1
SCHEMBL701660 0.83 TDP1 (0.45) MEN1KMT2AALDH1A1HPGDPOLB
SCHEMBL16601609 0.81 TDP1 (0.44) PRMT1MEN1KMT2AALDH1A1KEAP1
SCHEMBL16601984 0.81 TNF (0.39) PRMT1ALDH1A1KDM4EHPGDTERT
SCHEMBL16601612 0.80 PRMT1 (0.35) PRMT1MEN1KMT2AALDH1A1KEAP1
SCHEMBL16656165 0.76 CASP3 (0.41) PRMT1MEN1KMT2AALDH1A1KEAP1
SCHEMBL22893524 0.76 TDP1 (0.42) PRMT1MEN1KMT2AALDH1A1KDM4E
SCHEMBL10018474 0.76 PIN1 (0.36) ALDH1A1HPGDTERTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed