SCHEMBL16601624

SCHEMBL16601624

C/N=C1/C(=O)c2ccc(-c3ccccc3)c3c(-c4ccccc4)ccc1c23

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.37
PLK4 O00444 1/20 0.36
MAPK9 P45984 1/20 0.36
LIMK1 P53667 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
AKT3 Q9Y243 1/20 0.36
BACE1 P56817 2/20 0.35
PTPN1 P18031 3/20 0.35
MAPT P10636 3/20 0.35
HTT P42858 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
PTGS2 P35354 2/20 0.35
MEN1 O00255 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35
PTPRC P08575 1/20 0.35
PTPRF P10586 1/20 0.35
CDC25B P30305 1/20 0.35
APAF1 O14727 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14257723 0.80 LMNA (0.50) PLK4MAPK9LIMK1CLK4AKT3
SCHEMBL14393077 0.75 ALDH1A1 (0.64) MAPTHTTNPSR1MEN1RAB9A
SCHEMBL3872493 0.72 ALDH1A1 (0.53) PLK4MAPK9LIMK1CLK4AKT3
SCHEMBL16601687 0.70 KMT2A (0.32) PTPN1KMT2A
SCHEMBL9995145 0.68 ESR1 (0.44) PDE4BPLK4MAPK9LIMK1CLK4
SCHEMBL15119612 0.67 ALOX15 (0.52) PLK4MAPK9LIMK1CLK4AKT3
SCHEMBL16656171 0.64 ALDH1A1 (0.43) PLK4MAPK9LIMK1CLK4AKT3
SCHEMBL29444799 0.64 ALDH1A1 (0.42) PLK4MAPK9LIMK1CLK4AKT3
SCHEMBL27530459 0.64 LMNA (0.50) BACE1PTPN1MAPTHTTNPSR1
SCHEMBL27795692 0.64 ALDH1A1 (0.42) PLK4MAPK9LIMK1CLK4AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed