SCHEMBL9995145

SCHEMBL9995145

O=C1C(c2ccccc2)=C2C(=C1c1ccccc1)c1ccc(-c3ccccc3)c3c(-c4ccccc4)ccc2c13

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
P2RX7 Q99572 1/20 0.42
PDE4B Q07343 1/20 0.42
MAPT P10636 3/20 0.41
NPSR1 Q6W5P4 3/20 0.41
HTT P42858 2/20 0.41
FGFR1 P11362 2/20 0.41
FGFR2 P21802 2/20 0.41
FGFR4 P22455 2/20 0.41
FGFR3 P22607 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MITF O75030 1/20 0.41
KMT2A Q03164 3/20 0.41
PLK4 O00444 1/20 0.40
MAPK9 P45984 1/20 0.40
LIMK1 P53667 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
AKT3 Q9Y243 1/20 0.40
CDC25A P30304 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12413368 0.83 ALDH1A1 (0.41) ESR1ESR2P2RX7PDE4BMAPT
SCHEMBL14257723 0.81 LMNA (0.50) P2RX7MAPTNPSR1HTTALDH1A1
SCHEMBL22143430 0.79 FGFR1 (0.55) ESR1ESR2P2RX7PDE4BMAPT
SCHEMBL29773784 0.79 ALDH1A1 (0.56) P2RX7MAPTNPSR1HTTFGFR1
SCHEMBL75606 0.79 ALDH1A1 (0.56) P2RX7MAPTNPSR1HTTFGFR1
SCHEMBL12683614 0.79 ESR1 (0.40) ESR1ESR2P2RX7PDE4BMAPT
SCHEMBL516326 0.78 PDE4B (0.54) ESR1ESR2P2RX7PDE4BMAPT
SCHEMBL3872493 0.78 ALDH1A1 (0.53) ESR2ALDH1A1PLK4MAPK9LIMK1
SCHEMBL15028262 0.77 MAPT (0.47) ESR1ESR2P2RX7MAPTNPSR1
SCHEMBL10048166 0.77 ESR1 (0.39) ESR1ESR2P2RX7MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028976-B2 Organic EL device FUTABA CORPORATION (JP) 2015-05-12 US disclosed
US-20110295017-A1 Organic EL Device TDK CORPORATION (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295017-A1 Organic EL Device LEF1, ELP1, MLLT1 ESR1 16/4885ESR2 86/4885P2RX7 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.