Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | GRB2 | P62993 | 1/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 11/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313774 | 0.89 | KDM4E (0.65) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL4209634 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL10314004 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL10313775 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL533173 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL219274 | 0.77 | KDM4E (0.67) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL10313777 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL27777982 | 0.75 | HSD17B3 (0.60) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL12729968 | 0.75 | AKR1B1 (0.76) | KDM4EALDH1A1GAAGLALCK | |
| SCHEMBL723839 | 0.75 | LCK (0.76) | KDM4EALDH1A1GAAGLALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150253245-A1 | FLUORESCENT POLYMERS OF 7-HYDROXYCOUMARIN COMPOUNDS, CHEMICAL SENSORS COMPRISING THEM, AND POLYMERIZABLE FLUORESCENT COMPOUND OF 7-HYDROXYCOUMARIN | Commissariat a l'énergie atomique et aux énergies alternatives (FR) | 2015-09-10 | — | — | US | disclosed |
| US-8993700-B2 | Fluorescent polymers of 7-hydroxycoumarin compounds, chemical sensors comprising them, and polymerizable fluorescent compound of 7-hydroxycoumarin | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-03-31 | — | — | US | disclosed |