Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | GLA | P06280 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | HSD17B3 | P37058 | 10/20 | 0.70 |
| ▸ | LCK | P06239 | 2/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | GRB2 | P62993 | 1/20 | 0.70 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23132281 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL4209634 | 0.86 | KDM4E (0.76) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL14564349 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL7919714 | 0.85 | KDM4E (0.74) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL7919717 | 0.85 | KDM4E (0.74) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL13840541 | 0.84 | AKR1B1 (0.76) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL14399202 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL5433316 | 0.83 | KDM4E (0.71) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL29115101 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL263980 | 0.82 | AKR1B1 (1.00) | ALDH1A1KDM4EGLAGAAHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160003836-A1 | PHOTO OR CHEMOLABILE CONJUGATES FOR MOLECULES DETECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-01-07 | — | — | US | disclosed |
| US-20160003836-A1 | PHOTO OR CHEMOLABILE CONJUGATES FOR MOLECULES DETECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-01-07 | — | — | US | disclosed |
| US-20150253245-A1 | FLUORESCENT POLYMERS OF 7-HYDROXYCOUMARIN COMPOUNDS, CHEMICAL SENSORS COMPRISING THEM, AND POLYMERIZABLE FLUORESCENT COMPOUND OF 7-HYDROXYCOUMARIN | Commissariat a l'énergie atomique et aux énergies alternatives (FR) | 2015-09-10 | — | — | US | disclosed |
| US-8993700-B2 | Fluorescent polymers of 7-hydroxycoumarin compounds, chemical sensors comprising them, and polymerizable fluorescent compound of 7-hydroxycoumarin | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-03-31 | — | — | US | disclosed |
| WO-2014125112-A1 | PHOTO OR CHEMOLABILE CONJUGATES FOR MOLECULES DETECTION | IMABIOTECH (FR) | 2014-08-21 | — | — | WO | disclosed |
| EP-2767832-A1 | Photo or chemolabile conjugates for molecules detection | Imabiotech (FR) | 2014-08-20 | — | — | EP | disclosed |
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20120178172-A1 | FLUORESCENT POLYMERS OF 7-HYDROXYCOUMARIN COMPOUNDS, CHEMICAL SENSORS COMPRISING THEM, AND POLYMERIZABLE FLUORESCENT COMPOUND OF 7-HYDROXYCOUMARIN | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-07-12 | — | — | US | disclosed |
| EP-1235938-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | EPOCH BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002099141-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | US | disclosed |
| EP-1235938-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | Epoch Biosciences, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | ELITECHGROUP, INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2001042505-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| EP-1062361-A2 | WATER-SOLUBLE COUMARIN FLUORESCENT ENZYME SUBSTRATES | ABBOTT LABORATORIES (US) | 2000-12-27 | — | — | EP | disclosed |
| US-5998593-A | COUMARIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1999046402-A2 | WATER-SOLUBLE COUMARIN FLUORESCENT ENZYME SUBSTRATES | ABBOTT LABORATORIES (US) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | ALDH1A1 2350/4885KDM4E 4634/4885GLA 1490/4885 |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | ALDH1A1 2350/4885KDM4E 4634/4885GLA 1490/4885 |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | IPO4, PTBP3, DDX5 | ALDH1A1 3183/4885KDM4E 3864/4885GLA 4633/4885 |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | DCLRE1B, SNRPE, ZFR | ALDH1A1 2641/4885KDM4E 4757/4885GLA 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.