SCHEMBL16601642

SCHEMBL16601642

CCC(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccc(O)cc1)C3=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.62
APAF1 O14727 1/20 0.62
ESR1 P03372 5/20 0.48
ESR2 Q92731 3/20 0.48
NR1H3 Q13133 1/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
USP2 O75604 2/20 0.41
LMNA P02545 1/20 0.41
BRD4 O60885 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601671 0.88 POLB (0.48) POLBAPAF1ESR1ESR2NR1H3
SCHEMBL16601637 0.88 POLB (0.44) POLBAPAF1ESR1ALDH1A1KDM4E
SCHEMBL16866428 0.86 POLB (0.46) POLBAPAF1NR1H3ALDH1A1KDM4E
SCHEMBL16601646 0.85 KDM4E (0.41) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601678 0.83 ALDH1A1 (0.41) POLBAPAF1ESR1ESR2ALDH1A1
SCHEMBL24977256 0.81 POLB (0.51) POLBAPAF1ESR1ESR2NR1H3
SCHEMBL16866461 0.81 POLB (0.42) POLBAPAF1NR1H3ALDH1A1KDM4E
SCHEMBL16602028 0.81 PGR (0.40) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL18351295 0.81 KDM4E (0.40) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16870228 0.80 PPARA (0.47) POLBAPAF1NR1H3ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed