SCHEMBL16601637

SCHEMBL16601637

CCC(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccccc1)C3=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.44
APAF1 O14727 1/20 0.44
ALDH1A1 P00352 7/20 0.44
KDM4E B2RXH2 5/20 0.44
TDP1 Q9NUW8 2/20 0.44
APOBEC3A P31941 1/20 0.44
RECQL P46063 1/20 0.44
CASP6 P55212 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
RAB9A P51151 2/20 0.43
ESR1 P03372 1/20 0.43
NPC1 O15118 1/20 0.43
KMT2A Q03164 4/20 0.43
USP2 O75604 3/20 0.43
MEN1 O00255 3/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KEAP1 Q14145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601642 0.88 POLB (0.62) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601646 0.87 KDM4E (0.41) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601671 0.86 POLB (0.48) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601638 0.86 KMT2A (0.46) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601667 0.86 ALDH1A1 (0.46) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16866428 0.84 POLB (0.46) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601653 0.83 NPC1 (0.45) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601654 0.83 KMT2A (0.44) POLBAPAF1ALDH1A1KDM4EL3MBTL1
SCHEMBL18351295 0.82 KDM4E (0.40) POLBAPAF1ALDH1A1KDM4ETDP1
SCHEMBL16601678 0.81 ALDH1A1 (0.41) POLBAPAF1ALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed