SCHEMBL16601671

SCHEMBL16601671

CCC(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccc(CO)cc1)C3=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
HPGD P15428 1/20 0.48
CYP2C19 P33261 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
APAF1 O14727 1/20 0.45
PPARA Q07869 3/20 0.40
PPARD Q03181 2/20 0.40
PPARG P37231 1/20 0.40
CA9 Q16790 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
NR1H3 Q13133 3/20 0.37
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
DNM2 P50570 1/20 0.35
STAT3 P40763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16866428 0.90 POLB (0.46) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16601642 0.88 POLB (0.62) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16601637 0.86 POLB (0.44) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16866461 0.85 POLB (0.42) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16601646 0.84 KDM4E (0.41) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16870228 0.84 PPARA (0.47) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16601678 0.82 ALDH1A1 (0.41) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16866478 0.82 MEN1 (0.36) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16866465 0.81 POLB (0.39) POLBALDH1A1KDM4ECYP1A2HPGD
SCHEMBL16602028 0.80 PGR (0.40) POLBALDH1A1KDM4ECYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed