SCHEMBL16601654

SCHEMBL16601654

CCC(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccccc1O)C3=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.44
MEN1 O00255 7/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44
TLR9 Q9NR96 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
USP2 O75604 2/20 0.36
GAA P10253 2/20 0.36
CASP1 P29466 2/20 0.36
CASP7 P55210 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CRHBP P24387 1/20 0.36
BRCA1 P38398 1/20 0.36
HBB P68871 1/20 0.36
CRHR2 Q13324 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
APAF1 O14727 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601646 0.83 KDM4E (0.41) KMT2AMEN1HTTL3MBTL1GAA
SCHEMBL16601637 0.83 POLB (0.44) KMT2AMEN1MAPTHTTL3MBTL1
SCHEMBL16601643 0.80 MEN1 (0.60) KMT2AMEN1MAPTHTTTLR9
SCHEMBL16601642 0.79 POLB (0.62) KMT2AMEN1HTTUSP2ALDH1A1
SCHEMBL18351295 0.79 KDM4E (0.40) KMT2AMEN1HTTL3MBTL1GAA
SCHEMBL12657845 0.78 ANPEP (0.52) KMT2AMEN1MAPTHTTL3MBTL1
SCHEMBL24976834 0.78 MEN1 (0.40) KMT2AMEN1MAPTHTTL3MBTL1
SCHEMBL16601834 0.78 TERT (0.43) KMT2AMEN1HTTL3MBTL1USP2
SCHEMBL15241103 0.77 TDP1 (0.46) HTTL3MBTL1GAAALDH1A1HSD17B10
SCHEMBL7054656 0.77 TDP1 (0.46) HTTL3MBTL1GAAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed