SCHEMBL16601673

SCHEMBL16601673

CCc1cccc(CC)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1cc(CO)ccc1C)C3=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 4/20 0.51
DPP4 P27487 4/20 0.51
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CRHBP P24387 2/20 0.41
CRHR2 Q13324 2/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
CASP1 P29466 1/20 0.41
BRCA1 P38398 1/20 0.41
CASP7 P55210 1/20 0.41
HBB P68871 1/20 0.41
HSD17B10 Q99714 1/20 0.41
BRD1 O95696 6/20 0.40
TAF1 P21675 6/20 0.40
BRPF1 P55201 6/20 0.40
TAF1L Q8IZX4 1/20 0.40
CREBBP Q92793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12556946 0.80 ANPEP (0.55) ANPEPDPP4MEN1KMT2ACRHBP
SCHEMBL16602003 0.80 ALDH1A1 (0.48) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL22221562 0.79 ANPEP (0.66) ANPEPDPP4MEN1KMT2ACRHBP
SCHEMBL16866478 0.78 MEN1 (0.36) MEN1KMT2ACRHBPCRHR2MAPT
SCHEMBL16601832 0.78 ANPEP (0.50) ANPEPDPP4MEN1KMT2ACRHBP
SCHEMBL17715435 0.77 ANPEP (0.39) ANPEPDPP4CRHBPCRHR2MAPT
SCHEMBL13045764 0.76 DPP4 (0.55) ANPEPDPP4MEN1KMT2ACRHBP
SCHEMBL17263572 0.76 MEN1 (0.52) ANPEPDPP4MEN1KMT2ACRHBP
SCHEMBL16601811 0.76 ANPEP (0.50) ANPEPDPP4MEN1KMT2ACRHBP
SCHEMBL16601708 0.75 ANPEP (0.52) ANPEPDPP4MEN1KMT2ACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed