SCHEMBL16601692

SCHEMBL16601692

CCC(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1c(F)c(F)c(F)c(F)c1F)C3=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
APAF1 O14727 1/20 0.33
ANPEP P15144 2/20 0.33
DPP4 P27487 2/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PIN1 Q13526 1/20 0.32
PIN4 Q9Y237 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32
RGS12 O14924 1/20 0.32
LMNA P02545 1/20 0.32
PABPC1 P11940 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601824 0.95 TERT (0.35) POLBAPAF1ANPEPDPP4
SCHEMBL16601646 0.85 KDM4E (0.41) POLBAPAF1KDM4EALDH1A1CYP1A2
SCHEMBL12657845 0.83 ANPEP (0.52) POLBAPAF1ANPEPDPP4KDM4E
SCHEMBL21693565 0.83 GALR3 (0.33) POLBKDM4EALDH1A1CYP1A2HPGD
SCHEMBL18351295 0.81 KDM4E (0.40) POLBAPAF1KDM4EALDH1A1CYP1A2
SCHEMBL24976834 0.80 MEN1 (0.40) POLBKDM4EALDH1A1HPGDPIN1
SCHEMBL16601834 0.80 TERT (0.43) POLBAPAF1KDM4EALDH1A1CYP1A2
SCHEMBL21693414 0.80 GALR3 (0.32) GALR3
SCHEMBL16601637 0.80 POLB (0.44) POLBAPAF1KDM4EALDH1A1CYP1A2
SCHEMBL16601831 0.79 ANPEP (0.48) POLBANPEPDPP4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed