SCHEMBL16601824

SCHEMBL16601824

CCC(CO)N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(c1c(F)c(F)c(F)c(F)c1F)C5=O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TERT O14746 4/20 0.35
STAT3 P40763 1/20 0.33
HIF1A Q16665 1/20 0.33
APAF1 O14727 1/20 0.31
POLB P06746 1/20 0.31
ANPEP P15144 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601692 0.95 POLB (0.33) APAF1POLBANPEPDPP4
SCHEMBL16601834 0.87 TERT (0.43) TERTSTAT3HIF1AAPAF1POLB
SCHEMBL16601831 0.84 ANPEP (0.48) TERTSTAT3HIF1APOLBANPEP
SCHEMBL16601646 0.81 KDM4E (0.41) TERTAPAF1POLB
SCHEMBL15764232 0.81 DPP4 (0.42) TERTANPEPDPP4
SCHEMBL2222018 0.80 TERT (0.41) TERTSTAT3HIF1AAPAF1POLB
SCHEMBL21693565 0.79 GALR3 (0.33) POLB
SCHEMBL12657845 0.79 ANPEP (0.52) APAF1POLBANPEPDPP4
SCHEMBL305590 0.78 TERT (0.47) TERTSTAT3HIF1APOLB
SCHEMBL30195004 0.78 TERT (0.47) TERTSTAT3HIF1APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed