SCHEMBL16601701

SCHEMBL16601701

O=C1C(=O)c2ccc(-c3ccc(O)cc3)nc2-c2ncccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.56
NSD2 O96028 2/20 0.56
PAX8 Q06710 2/20 0.56
ABL1 P00519 1/20 0.56
PLCG1 P19174 1/20 0.56
CES1 P23141 1/20 0.56
RIN1 Q13671 1/20 0.56
GAA P10253 1/20 0.51
PTPRC P08575 2/20 0.47
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47
PTPN13 Q12923 1/20 0.47
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
HPGDS O60760 1/20 0.44
PKM P14618 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601685 0.87 MAPT (0.50) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL16602054 0.85 TDP2 (0.40) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL15764216 0.85 TDP2 (0.56) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL31402361 0.83 GAA (0.61) TDP2NSD2PAX8ABL1PLCG1
Phenol SCHEMBL29219006 0.77 TDP2 (0.73) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL16601733 0.77 TDP2 (0.56) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL15764215 0.76 TDP2 (0.47) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL29419580 0.75 TDP2 (1.00) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL460433 0.75 TDP2 (1.00) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL31460555 0.73 RAB9A (0.48) PTPRCCTSLCTSSPTPN13MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed