SCHEMBL16601685

SCHEMBL16601685

O=C1C(=O)c2ccc(-c3ccc(O)cc3)nc2-c2nc(-c3ccc(O)cc3)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
HPGD P15428 1/20 0.50
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HPGDS O60760 1/20 0.46
PKM P14618 1/20 0.46
MAOB P27338 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ESR2 Q92731 7/20 0.46
ESR1 P03372 6/20 0.46
AR P10275 1/20 0.46
SENP1 Q9P0U3 1/20 0.41
ALK Q9UM73 1/20 0.40
NTSR1 P30989 1/20 0.39
LTA4H P09960 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601701 0.87 TDP2 (0.56) MAPTHSD17B10ALDH1A1POLBHPGD
SCHEMBL16602015 0.82 MAPT (0.38) MAPTHSD17B10ALDH1A1POLBHPGD
SCHEMBL31460555 0.80 RAB9A (0.48) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL16656190 0.75 S100A4 (0.43) HSD17B10ALDH1A1POLBHPGDMEN1
SCHEMBL2342050 0.73 MAPT (0.60) MAPTHSD17B10ALDH1A1POLBHPGD
SCHEMBL31403406 0.73 MAPT (0.60) MAPTHSD17B10ALDH1A1POLBHPGD
SCHEMBL31403407 0.73 MAPT (0.60) MAPTHSD17B10ALDH1A1POLBHPGD
SCHEMBL4049450 0.72 RAB9A (0.54) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL15764216 0.71 TDP2 (0.56) MAPTMEN1KMT2A
SCHEMBL8675465 0.70 MAPT (0.59) MAPTALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed