Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601746 | 0.84 | ALDH1A1 (0.40) | LRRK2ALDH1A1MEN1POLBGAA | |
| SCHEMBL16601705 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL66152 | 0.70 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTMAPK1HSD17B10 | |
| SCHEMBL16656346 | 0.70 | FYN (0.42) | LRRK2ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL16601752 | 0.70 | FYN (0.42) | LRRK2ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL16601755 | 0.67 | ALDH1A1 (0.68) | ALDH1A1CYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL16601719 | 0.65 | MAPT (0.46) | LRRK2ALDH1A1CYP1A2CYP3A4MEN1 | |
| SCHEMBL16601723 | 0.64 | ALDH1A1 (0.45) | LRRK2ALDH1A1CYP1A2CYP3A4MEN1 | |
| SCHEMBL16656210 | 0.64 | ALDH1A1 (0.45) | LRRK2ALDH1A1CYP1A2CYP3A4MEN1 | |
| SCHEMBL19698857 | 0.63 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP3A4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |