Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601752 | 1.00 | FYN (0.42) | FYNLRRK2HTR7ALDH1A1AOC3 | |
| SCHEMBL16601753 | 0.80 | MAPT (0.41) | TSHRCNR2MEN1CASP3RAB9A | |
| SCHEMBL16656340 | 0.80 | MAPT (0.41) | TSHRCNR2MEN1CASP3RAB9A | |
| SCHEMBL16656351 | 0.80 | MAPT (0.47) | LRRK2ALDH1A1CNR2MEN1RAB9A | |
| SCHEMBL16601726 | 0.80 | MAPT (0.47) | LRRK2ALDH1A1CNR2MEN1RAB9A | |
| SCHEMBL16601758 | 0.74 | ALDH1A1 (0.46) | FYNALDH1A1TSHRHSD17B10CNR2 | |
| SCHEMBL16601744 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1NPC1KMT2A | |
| SCHEMBL7326388 | 0.72 | AOC3 (0.58) | FYNLRRK2AOC3APPPRKCI | |
| SCHEMBL16601704 | 0.70 | LRRK2 (0.40) | LRRK2ALDH1A1AOC3APPTDP1 | |
| SCHEMBL16601707 | 0.69 | MMP3 (0.35) | FYNHTR7PRKCICNR2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2680077-B1 | Electrophotographic photosensitive member, process catridge, and electrophotographic apparatus | CANON KK (JP) | 2015-10-28 | — | — | EP | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |