SCHEMBL66152

SCHEMBL66152

CN(C)c1ccc(CCO)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
TSHR P16473 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
CYP3A4 P08684 1/20 0.58
MAPK1 P28482 1/20 0.58
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA2 P00918 1/20 0.52
CALM1 P0DP23 2/20 0.50
CHKA P35790 3/20 0.47
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
SLC2A1 P11166 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596165 0.86 ALDH1A1 (0.54) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL4405018 0.85 ALDH1A1 (0.70) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL31186833 0.85 CHKA (0.55) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL25305224 0.83 CHKA (0.53) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL8752395 0.82 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL165131 0.80 ALDH1A1 (0.64) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL6310153 0.80 ALDH1A1 (0.64) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL40656 0.79 CA2 (0.77) ALDH1A1TSHRTDP1CA2CYP4F2
SCHEMBL14053392 0.79 CYP4A11 (0.47) TSHRTDP1ALOX15CA2CYP4F2
SCHEMBL171763 0.78 ALDH1A1 (0.61) ALDH1A1TSHRTDP1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3700465-B1 ENDOLUMINAL DEVICE AND POLYMER ENDOLOGIX LLC (US) 2025-07-16 EP claimed
WO-2025093205-A1 TWO COMPONENT (2K) CURABLE AND DEBONDABLE ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2025-05-08 WO claimed
US-20250107971-A1 POWDER-LIQUID-TYPE DENTAL PLATE LINER TOKUYAMA DENTAL CORPORATION (JP) 2025-04-03 US claimed
US-12240973-B2 Endoluminal device and polymer ENDOLOGIX LLC (US) 2025-03-04 US claimed
EP-4464302-A1 POWDER-LIQUID-TYPE DENTURE BASE LINER Tokuyama Dental Corporation (JP) 2024-11-20 EP claimed
CN-118541125-A Lining material for powder-liquid denture base 德山齿科株式会社 2024-08-23 CN claimed
CN-117321088-A Preparation of monodisperse Polymer beads by Room temperature initiation 深圳华大基因科技有限公司 2023-12-29 CN claimed
CN-114174238-B Low odor and low emission particulate materials and related coatings 赛德克公众有限公司 2023-05-05 CN claimed
WO-2022268544-A1 MATERIAL SYSTEM FOR 3D PRINTING EVONIK OPERATIONS GMBH (DE) 2022-12-29 WO claimed
WO-2022268545-A1 MATERIAL SYSTEM FOR 3D PRINTING EVONIK OPERATIONS GMBH (DE) 2022-12-29 WO claimed
US-5738843-A POLYMERIZED METHACRYLATE LIQUID BINDER OPI PRODUCTS, INC. (US) 1998-04-14 US claimed
US-5603924-A LIQUID BINDER CONTAINING MONOMERIC (METH)ACRYLATE, OPTIONAL CROSSLINKER, ALCOHOL, AND TERTIARY AMINE ACCELERATOR, FILLER OF POLYMER AND ORGANIC PEROXIDE INITIATOR; FAST CURING OPI PRODUCTS, INC. 1997-02-18 US claimed
US-5268396-A Organosilicon soft denture liners LAI JUEY H (US) 1993-12-07 US claimed
EP-0361408-B1 Improved bone cement WOLLF & KAABER AS (DK) 1993-11-24 EP claimed
US-5098696-A Methacrylate monomers for polymers with tert-amine promoters and di or trimethacrylate monomers and peroxide catalysts REM SYSTEMS, INC. (US) 1992-03-24 US claimed
WO-1990003193-A1 BONE CEMENT WOLFF & KAABER A/S (DK) 1990-04-05 WO claimed
EP-0361408-A2 Improved bone cement Wolff & Kaaber A/S (DK) 1990-04-04 EP claimed
US-4910259-A Acrylated polymer WOLFF & KAABER A/S (DK) 1990-03-20 US claimed
US-4871534-A METHACRYLATE BINDER, METHACRYLATE POLYMER, PEROXIDE INITIATOR REM SYSTEMS, INC. (US) 1989-10-03 US claimed
US-4284551-A PROMOTERS FOR CURING AND POLYMERIZATION OF METHACRYLATES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1981-08-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250107971-A1 POWDER-LIQUID-TYPE DENTAL PLATE LINER HEATR1, HEATR6, ACTR5 ALDH1A1 2486/4885TSHR 1220/4885TDP1 2546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.