SCHEMBL16601744

SCHEMBL16601744

OCc1ccc(N=C2c3ccccc3-c3c2cccc3-c2ccc(O)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
ABL1 P00519 1/20 0.36
ABCB1 P08183 1/20 0.36
BCR P11274 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
PKM P14618 1/20 0.35
BLM P54132 1/20 0.35
PLEC Q15149 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ESR2 Q92731 1/20 0.33
MGAM O43451 4/20 0.33
GAA P10253 4/20 0.33
SI P14410 4/20 0.33
MGAM2 Q2M2H8 4/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601758 0.84 ALDH1A1 (0.46) ALDH1A1TSHRPDCD1CD274
SCHEMBL16601755 0.80 ALDH1A1 (0.68) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL16601743 0.77 MEN1 (0.49) ALDH1A1ESR2MEN1KMT2ATSHR
SCHEMBL16601699 0.75 S100A4 (0.48) ALDH1A1MAPTTHRBPKMMEN1
SCHEMBL16601698 0.75 ALDH1A1 (0.77) ALDH1A1ABL1ABCB1BCRKDM4E
SCHEMBL16656346 0.74 FYN (0.42) ALDH1A1MEN1NPC1KMT2ATSHR
SCHEMBL16601752 0.74 FYN (0.42) ALDH1A1MEN1NPC1KMT2ATSHR
SCHEMBL16601726 0.72 MAPT (0.47) ALDH1A1MAPTPKMMEN1KMT2A
Parahydroxybenzyl Alcohol SCHEMBL28122521 0.71 BCL2L1 (0.48) ALDH1A1ABL1ABCB1BCRKDM4E
SCHEMBL29078081 0.71 CASP3 (0.53) ALDH1A1ABL1ABCB1BCRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed