Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 7/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764229 | 0.83 | MEN1 (0.36) | HSD17B3MAOAMAOBCDC25BLMNA | |
| SCHEMBL16601789 | 0.82 | HSD17B3 (0.46) | HSD17B3MAOAMAOBGAAKDM4E | |
| SCHEMBL21887168 | 0.79 | MAOA (0.72) | HSD17B3MAOAMAOBBACE1PTPN1 | |
| SCHEMBL15764225 | 0.74 | BACE1 (0.68) | MAOAMAOBBACE1PTPN1PTPRC | |
| SCHEMBL16601629 | 0.74 | BACE1 (0.48) | HSD17B3MAOAMAOBBACE1PTPN1 | |
| SCHEMBL134702 | 0.74 | BACE1 (0.73) | HSD17B3MAOAMAOBBACE1PTPN1 | |
| SCHEMBL16601799 | 0.72 | EPHX2 (0.47) | TSHRMAPT | |
| SCHEMBL17208874 | 0.71 | KDM4E (0.37) | HSD17B3MAOAMAOBBACE1KDM4E | |
| SCHEMBL16601798 | 0.70 | HSD17B3 (0.32) | HSD17B3MAOAMAOBGAAKDM4E | |
| SCHEMBL16601791 | 0.69 | BACE1 (0.50) | HSD17B3MAOAMAOBBACE1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |