Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160580 | 0.84 | BACE1 (0.57) | BACE1MAOAMAOBPTPN1CDC25B | |
| SCHEMBL14922782 | 0.84 | PTGS2 (0.34) | BACE1HSD17B3MAPK1MAPTPKM | |
| SCHEMBL134702 | 0.80 | BACE1 (0.73) | BACE1MAOAMAOBPTPN1CDC25B | |
| SCHEMBL21887168 | 0.78 | MAOA (0.72) | BACE1MAOAMAOBPTPN1CDC25B | |
| SCHEMBL16656179 | 0.76 | MAPT (0.43) | BACE1MAOAMAOBHSD17B3MAPK1 | |
| SCHEMBL12112009 | 0.75 | EEF2K (0.37) | MAOAMAOBCDC25BMAPK1LMNA | |
| SCHEMBL20824938 | 0.75 | EEF2K (0.37) | MAOAMAOBCDC25BMAPK1LMNA | |
| SCHEMBL16601763 | 0.74 | HSD17B3 (0.49) | BACE1MAOAMAOBPTPN1CDC25B | |
| Biphenyl SCHEMBL28097686 | 0.72 | HSD17B3 (0.59) | BACE1MAOAMAOBPTPN1CDC25B | |
| SCHEMBL13903839 | 0.71 | BACE1 (0.39) | BACE1MAOAMAOBPTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |