Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601826 | 0.86 | POLB (0.43) | KMT2AMEN1NR1H3ALDH1A1KDM4E | |
| SCHEMBL12577485 | 0.83 | NR1H3 (0.56) | KMT2AMEN1NR1H3ESR1ALDH1A1 | |
| SCHEMBL29355675 | 0.83 | ESR1 (0.59) | KMT2AMEN1NR1H3ESR1ALDH1A1 | |
| SCHEMBL3404909 | 0.83 | ESR1 (0.59) | KMT2AMEN1NR1H3ESR1ALDH1A1 | |
| SCHEMBL30720985 | 0.83 | ESR1 (0.59) | KMT2AMEN1NR1H3ESR1ALDH1A1 | |
| SCHEMBL16417481 | 0.80 | NR1H2 (0.50) | KMT2AMEN1NR1H3ALDH1A1MAPT | |
| SCHEMBL7647376 | 0.79 | KMT2A (0.58) | KMT2AMEN1NR1H3ESR1ALDH1A1 | |
| SCHEMBL16601811 | 0.79 | ANPEP (0.50) | KMT2AMEN1NR1H3ALDH1A1KDM4E | |
| SCHEMBL15672159 | 0.78 | ESR1 (0.57) | KMT2AMEN1NR1H3ESR1ALDH1A1 | |
| SCHEMBL5578422 | 0.78 | ESR1 (0.54) | KMT2AMEN1NR1H3ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |