SCHEMBL16601833

SCHEMBL16601833

CCc1cccc(C)c1N1C(=O)c2ccc3c4ccc5c6c(cc(C(=O)O)c(c7ccc(c2c37)C1=O)c64)C(=O)N(c1c(C)cccc1CC)C5=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 4/20 0.44
DPP4 P27487 4/20 0.44
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 3/20 0.40
POLB P06746 3/20 0.38
CASP6 P55212 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TYMS P04818 2/20 0.36
APEX1 P27695 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601820 0.82 TYMS (0.56) ANPEPDPP4ALDH1A1KDM4EPOLB
SCHEMBL16601631 0.81 DPP4 (0.46) ANPEPDPP4ALDH1A1KDM4EPOLB
SCHEMBL13045764 0.80 DPP4 (0.55) ANPEPDPP4ALDH1A1KDM4EPOLB
SCHEMBL8070665 0.77 ANPEP (0.59) ANPEPDPP4ALDH1A1KDM4EPOLB
SCHEMBL16601825 0.77 DPP4 (0.43) ANPEPDPP4ALDH1A1MAPTHSD17B10
SCHEMBL16601804 0.76 KDM4E (0.51) ANPEPDPP4ALDH1A1KDM4ETDP1
SCHEMBL15764232 0.75 DPP4 (0.42) ANPEPDPP4ALDH1A1MAPTHSD17B10
SCHEMBL12656452 0.75 DPP4 (0.50) ANPEPDPP4ALDH1A1KDM4EPOLB
SCHEMBL16601823 0.75 ANPEP (0.38) ANPEPDPP4ALDH1A1MAPTHTT
SCHEMBL16601812 0.74 HTT (0.53) ANPEPDPP4ALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed