SCHEMBL16601845

SCHEMBL16601845

O=C1c2cccc(CCO)c2C(=O)c2c(CCCCCCO)cccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.47
CTSG P08311 5/20 0.47
TERT O14746 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PABPC1 P11940 1/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2311538 0.90 MAOA (0.50) ELANECTSGTDP1MAOAMAOB
SCHEMBL16656220 0.89 ELANE (0.60) ELANECTSGTDP1MAOAMAOB
SCHEMBL2313485 0.84 MAOA (0.48) ELANECTSGTDP1MAOAMAOB
SCHEMBL2316204 0.83 MEN1 (0.54) ELANETDP1MAOAMAOBALDH1A1
SCHEMBL16656222 0.82 MAOA (0.67) ELANECTSGTDP1MAOAMAOB
SCHEMBL12096345 0.78 ELANE (0.62) ELANECTSG
SCHEMBL29393629 0.77 ADORA2A (0.52) TDP1MAOAMAOBALDH1A1LMNA
SCHEMBL124078 0.77 ADORA2A (0.52) TDP1MAOAMAOBALDH1A1LMNA
SCHEMBL16656213 0.77 MAOA (0.66) ELANECTSGTDP1MAOAMAOB
SCHEMBL17633986 0.76 KDM4E (0.41) ELANECTSGALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed