SCHEMBL16656222

SCHEMBL16656222

O=C1c2cccc(O)c2C(=O)c2c(CCO)cccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.67
ALDH1A1 P00352 3/20 0.67
MAPT P10636 3/20 0.67
TSHR P16473 3/20 0.67
TDP1 Q9NUW8 3/20 0.67
MAOB P27338 2/20 0.67
MAPK1 P28482 2/20 0.67
LMNA P02545 2/20 0.67
HPGD P15428 2/20 0.67
ALOX15 P16050 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
HSD17B10 Q99714 2/20 0.67
HTT P42858 1/20 0.67
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
EPHX2 P34913 1/20 0.56
ELANE P08246 8/20 0.56
CTSG P08311 7/20 0.56
KDM4E B2RXH2 2/20 0.51
CYP3A4 P08684 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656213 0.95 MAOA (0.66) MAOAALDH1A1MAPTTSHRTDP1
SCHEMBL2311538 0.91 MAOA (0.50) MAOAALDH1A1MAPTTSHRTDP1
SCHEMBL16656220 0.88 ELANE (0.60) MAOAALDH1A1MAPTTSHRTDP1
SCHEMBL2313485 0.86 MAOA (0.48) MAOAALDH1A1MAPTTSHRTDP1
SCHEMBL2316204 0.84 MEN1 (0.54) MAOAALDH1A1MAPTTSHRTDP1
SCHEMBL16601845 0.82 ELANE (0.47) MAOAALDH1A1MAPTTSHRTDP1
Danthron SCHEMBL83688 0.82 MAPT (1.00) MAOAALDH1A1MAPTTSHRTDP1
Danthron SCHEMBL30544826 0.82 MAPT (1.00) MAOAALDH1A1MAPTTSHRTDP1
Danthron SCHEMBL29356886 0.82 MAPT (1.00) MAOAALDH1A1MAPTTSHRTDP1
Danthron SCHEMBL30721499 0.80 MAPT (0.95) MAOAALDH1A1MAPTTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed