Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.52 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.52 |
| ▸ | FGR | P09769 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393629 | 1.00 | ADORA2A (0.52) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL2313485 | 0.88 | MAOA (0.48) | ADORA2AMAOAMEN1KMT2APOLB | |
| SCHEMBL2311538 | 0.86 | MAOA (0.50) | ADORA2AMAOAMEN1KMT2ATDP1 | |
| SCHEMBL2316204 | 0.83 | MEN1 (0.54) | ADORA2AMAOAMEN1KMT2APOLB | |
| SCHEMBL15293053 | 0.81 | ELANE (0.50) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL16656213 | 0.80 | MAOA (0.66) | MAOAMEN1KMT2APOLBTDP1 | |
| SCHEMBL15764237 | 0.79 | KMT2A (0.43) | ADORA2AMAOAMEN1KMT2APABPC1 | |
| SCHEMBL16656222 | 0.79 | MAOA (0.67) | MAOAMEN1KMT2APOLBTDP1 | |
| SCHEMBL15292226 | 0.78 | ADORA2A (0.45) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL16601845 | 0.77 | ELANE (0.47) | MAOAMEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| US-20050183213-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one quinone direct dye, and process using this composition | L'OREAL S.A. (FR) | 2005-08-25 | — | — | US | claimed |
| EP-1559411-A1 | Composition for dying keratinic fibers containing an alcohol oxidase and a quinonic dye, and the method for use of the composition | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| CN-118043027-A | Process for dyeing and/or lightening keratin fibres | 莱雅公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | L'OREAL (FR) | 2024-02-13 | — | — | US | disclosed |
| CN-117479916-A | Composition comprising at least one alkyl (poly) glycoside, at least one fatty alcohol, at least one fatty acid and at least one alkaline agent | 欧莱雅 | 2024-01-30 | — | — | CN | disclosed |
| CN-117425466-A | Cosmetic composition comprising at least one alkyl (poly) glycoside, N-dicarboxymethyl glutamic acid, propane-1, 3-diol, at least one fatty substance other than fatty acid, at least one dye | 欧莱雅 | 2024-01-19 | — | — | CN | disclosed |
| CN-117425465-A | Composition comprising N, N-dicarboxymethyl glutamic acid, at least one fatty alcohol, at least one fatty acid, at least one polyol, at least one alkaline agent and optionally at least one dye | 欧莱雅 | 2024-01-19 | — | — | CN | disclosed |
| US-11857662-B2 | Hair coloring compositions and methods thereof | KAO USA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | disclosed |
| EP-1312344-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312343-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL S.A. (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | KRT18, CKAP4, KRTCAP2 | ADORA2A 4851/4885MAOA 1906/4885CSNK1A1 418/4885 |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | ADORA2A 4730/4885MAOA 2154/4885CSNK1A1 246/4885 |
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | KRT18, DPYD, CKAP4 | ADORA2A 4423/4885MAOA 2261/4885CSNK1A1 54/4885 |
| US-11857662-B2 | Hair coloring compositions and methods thereof | SPAG5, ACR, MUC1 | ADORA2A 2563/4885MAOA 1942/4885CSNK1A1 3703/4885 |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | ADORA2A 4183/4885MAOA 281/4885CSNK1A1 1265/4885 |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | KRT18, TUBB3, TUBA3E | ADORA2A 4638/4885MAOA 1945/4885CSNK1A1 365/4885 |
| US-20050183213-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one quinone direct dye, and process using this composition | KRT18, ADH5, ADH1A | ADORA2A 4809/4885MAOA 71/4885CSNK1A1 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.