Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601935 | 0.99 | NAAA (0.45) | NAAAHTR2CLTA4HCYP1A2ALDH1A1 | |
| SCHEMBL8738810 | 0.90 | HTR2C (0.51) | NAAAHTR2CALDH1A1PRSS1PRSS2 | |
| SCHEMBL10099923 | 0.87 | ALDH1A1 (0.40) | HTR2CLTA4HCYP1A2ALDH1A1LMNA | |
| SCHEMBL10099921 | 0.79 | ACHE (0.38) | NAAAHTR2CLTA4HLMNAPRSS1 | |
| SCHEMBL17069546 | 0.78 | ACHE (0.31) | HTR2C | |
| SCHEMBL16929670 | 0.77 | HTR2C (0.58) | NAAAHTR2CALDH1A1PRSS1PRSS2 | |
| SCHEMBL8739243 | 0.77 | ACHE (0.31) | HTR2C | |
| SCHEMBL16140053 | 0.76 | ACHE (0.30) | HTR2C | |
| SCHEMBL11236824 | 0.76 | HTR2C (0.61) | NAAAHTR2CALDH1A1PRSS1PRSS2 | |
| SCHEMBL11228989 | 0.76 | HTR2C (0.61) | NAAAHTR2CALDH1A1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |