Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16604667 | 0.76 | TP53 (0.46) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL12010036 | 0.76 | KMT2A (0.55) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL3437395 | 0.68 | KMT2A (0.46) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL13420844 | 0.67 | CYP3A4 (0.46) | GAATHRBMAPTKMT2AL3MBTL1 | |
| SCHEMBL10029205 | 0.66 | KMT2A (0.44) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL12127525 | 0.66 | ALDH1A1 (0.68) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL9312746 | 0.64 | KMT2A (1.00) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL19392610 | 0.64 | SERPINE1 (0.58) | MAPTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL16303386 | 0.64 | KMT2A (0.77) | GAATHRBMAPTKMT2ATP53 | |
| SCHEMBL6360691 | 0.64 | KMT2A (0.77) | GAATHRBMAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150094284-A1 | S-TRIAZOLYL ALPHA-MERCAPTO ACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | ARDEA BIOSCIENCES, INC. | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094284-A1 | S-TRIAZOLYL ALPHA-MERCAPTO ACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | SPR, POLR2H, TST | GAA 610/4885THRB 1820/4885MAPT 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.