SCHEMBL16605161

SCHEMBL16605161

Cc1ccc(-c2ccc(-c3cccnc3)c(C)c2)c(CCC(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 1/20 0.49
▸ CCNC P24863 1/20 0.47
▸ CDK8 P49336 1/20 0.47
▸ FFAR1 O14842 3/20 0.47
▸ MKNK1 Q9BUB5 1/20 0.43
▸ MKNK2 Q9HBH9 1/20 0.43
▸ PDE3B Q13370 1/20 0.43
▸ PDE3A Q14432 1/20 0.43
▸ PTGER1 P34995 1/20 0.43
▸ PTGER4 P35408 1/20 0.43
▸ PTGER3 P43115 1/20 0.43
▸ PTGER2 P43116 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ CYP17A1 P05093 1/20 0.42
▸ PPARG P37231 1/20 0.42
▸ PPARD Q03181 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16605159 0.89 CCNC (0.46) SLC2A1CCNCCDK8FFAR1PTGER1
SCHEMBL1801441 0.87 CYP11B2 (0.52) SLC2A1CCNCCDK8FFAR1NPC1
SCHEMBL16605158 0.87 FFAR1 (0.54) FFAR1PTGER1PTGER4PTGER3PTGER2
SCHEMBL16605162 0.84 FFAR1 (0.47) FFAR1PTGER1PTGER4PTGER3PTGER2
SCHEMBL16863732 0.80 POLB (0.48) FFAR1PTGER1PTGER4PTGER3PTGER2
SCHEMBL19209442 0.79 SLC2A1 (0.53) SLC2A1CCNCCDK8MKNK1MKNK2
SCHEMBL1892708 0.79 FFAR1 (0.52) FFAR1PTGER1PTGER4PTGER3PTGER2
SCHEMBL1804118 0.77 CCNC (0.47) CCNCCDK8MKNK1MKNK2PTGER1
SCHEMBL15959119 0.77 ESR2 (0.56) FFAR1PTGER1PTGER4PTGER3PTGER2
SCHEMBL13393530 0.76 NPC1 (0.64) SLC2A1MKNK1MKNK2PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204197-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes FIBROSTATIN S L (ES) 2017-07-20 — — US disclosed
US-20150320730-A1 GPBP-1 inhibition and its therapeutic use FIBROSTATIN, S.L. (ES) 2015-11-12 — — US disclosed
US-9066938-B2 GPBP-1 inhibition and its therapeutic use Fibrostein, S.L. (ES) 2015-06-30 — — US disclosed
US-20150093378-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes FIBROSTATIN, S.L. (ES) 2015-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204197-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes CD2BP2, SAP30BP, LY96 SLC2A1 201/4885CCNC 3192/4885CDK8 2689/4885
US-20150093378-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes CD2BP2, SAP30BP, LY96 SLC2A1 201/4885CCNC 3192/4885CDK8 2689/4885
US-20150320730-A1 GPBP-1 inhibition and its therapeutic use ABCC1, ABCC8, ABCB1 SLC2A1 54/4885CCNC 715/4885CDK8 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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