SCHEMBL16605162

SCHEMBL16605162

Cc1ccc(-c2ccc(-c3ccc(C)c(C)c3)c(C)c2)c(CCC(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 9/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.46
▸ PTGER1 P34995 2/20 0.43
▸ PTGER4 P35408 2/20 0.43
▸ PTGER3 P43115 2/20 0.43
▸ PTGER2 P43116 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ FFAR4 Q5NUL3 7/20 0.42
▸ EPHB4 P54760 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ TP53 P04637 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ DDAH1 O94760 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16863732 0.90 POLB (0.48) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL16605158 0.89 FFAR1 (0.54) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL12660792 0.84 POLB (0.52) FFAR1NPSR1PTGER4PTGER3FFAR4
SCHEMBL16605161 0.84 SLC2A1 (0.49) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL69559 0.82 NPSR1 (0.57) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL1892708 0.81 FFAR1 (0.52) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL3670598 0.78 NPSR1 (0.68) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL29636581 0.78 NPSR1 (0.68) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL15959119 0.78 ESR2 (0.56) FFAR1NPSR1PTGER1PTGER4PTGER3
SCHEMBL1889009 0.78 FFAR1 (0.54) FFAR1PTGER1PTGER4PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204197-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes FIBROSTATIN S L (ES) 2017-07-20 — — US disclosed
US-20150320730-A1 GPBP-1 inhibition and its therapeutic use FIBROSTATIN, S.L. (ES) 2015-11-12 — — US disclosed
US-9066938-B2 GPBP-1 inhibition and its therapeutic use Fibrostein, S.L. (ES) 2015-06-30 — — US disclosed
US-20150093378-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes FIBROSTATIN, S.L. (ES) 2015-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204197-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes CD2BP2, SAP30BP, LY96 FFAR1 3034/4885NPSR1 2756/4885PTGER1 2343/4885
US-20150093378-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes CD2BP2, SAP30BP, LY96 FFAR1 3034/4885NPSR1 2756/4885PTGER1 2343/4885
US-20150320730-A1 GPBP-1 inhibition and its therapeutic use ABCC1, ABCC8, ABCB1 FFAR1 2553/4885NPSR1 3716/4885PTGER1 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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