Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495326 | 0.80 | CALM1 (0.50) | SMN1; SMN2CALM1 | |
| SCHEMBL9254321 | 0.80 | CALM1 (0.47) | SMN1; SMN2CALM1FDPSTNFFAAH | |
| SCHEMBL7914446 | 0.79 | NFKB1 (0.60) | CYP3A4TSHRNFKB1FDPSPPARG | |
| SCHEMBL7354913 | 0.79 | PDE4D (0.41) | CALM1PPARGPPARAPDE4D | |
| SCHEMBL6055497 | 0.79 | PDE4D (0.48) | CYP3A4TSHRSMN1; SMN2CALM1PDE4D | |
| SCHEMBL17832225 | 0.77 | PPARG (0.55) | SMN1; SMN2FDPSPPARGPPARDPPARA | |
| SCHEMBL14243155 | 0.77 | FDPS (0.55) | SMN1; SMN2FDPSPPARGPPARDPPARA | |
| SCHEMBL10080328 | 0.77 | SMPD1 (0.48) | FDPSPPARGPPARDPPARAPDE4D | |
| SCHEMBL12016738 | 0.76 | FDPS (0.54) | SMN1; SMN2CALM1FDPSPPARGPPARD | |
| SCHEMBL7333971 | 0.76 | SMPD1 (0.50) | SMN1; SMN2CALM1FDPSPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044470-A1 | NOVEL ANTI-INFLAMMATORY AGENTS BASED ON POLYPHENOLS OF THE OLIVE TREE | UNVIERSIDAD DE SEVILLA (ES) | 2015-04-02 | — | — | WO | disclosed |