Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623381 | 0.84 | MAOB (0.46) | CYP51A1MAOBAOC3MAOAKDM4E | |
| SCHEMBL16609253 | 0.83 | ADRB2 (0.47) | CYP51A1KDM4ETAAR1 | |
| SCHEMBL16609244 | 0.82 | TSHR (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16609252 | 0.78 | ADRB2 (0.43) | CYP51A1 | |
| SCHEMBL20371139 | 0.78 | TAAR1 (0.63) | MAOBAOC3MAOAKDM4ETAAR1 | |
| SCHEMBL9813896 | 0.76 | OPRK1 (0.51) | CYP51A1AOC3KDM4ETAAR1ALDH1A1 | |
| SCHEMBL7116379 | 0.76 | KDM4E (0.47) | MAOBAOC3MAOAKDM4ETAAR1 | |
| SCHEMBL7116373 | 0.76 | KDM4E (0.47) | MAOBAOC3MAOAKDM4ETAAR1 | |
| SCHEMBL31361992 | 0.75 | AOC3 (0.42) | MAOBAOC3MAOAKDM4ETAAR1 | |
| SCHEMBL9641990 | 0.75 | KDM4E (0.54) | CYP51A1AOC3KDM4ETAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |